A single dose of kudzu extract reduces alcohol consumption in a binge drinking paradigm

Kudzu root is linked to a wide range of potential health benefits from easing menopausal symptoms to treating alcohol dependence. Still, more research needs to be done to prove whether it’s truly effective. Acute alcohol administration resulted in expected, dose-related alterations in subjective, psychomotor, cognitive, and physiological effects. These effects typically were greater after the higher dose, and the time course kudzu extract for alcoholism follows the known effects of alcohol (Brasser et al., 2004; Holdstock et al., 2000). Subjective measures of alcohol intoxication were greatest at 30 minutes and returned to or were close to predrinking levels by the end of the assessment period (3 hours). Psychomotor (stance stability/body sway) and cognitive function were most affected at 60 minutes, and they too returned to or were close to baseline by 3 hours.

  • Studies have shown that kudzu may work by increasing blood flow to the brain, reducing the desire to drink, and reducing the severity of hangovers.
  • McLean Hospital has licensed the production of kudzu extract (NPI-031) to Natural Pharmacie International (NPI), Inc. and they are marketing it as Alkontrol-Herbal®.
  • The present study was conducted in nontreatment-seeking heavy drinkers to assess the safety and efficacy of 4 weeks of kudzu extract in an outpatient setting.
  • PPAR is a nuclear receptor that plays a regulatory role in the expression of genes related to preadipocyte differentiation, insulin sensitivity, and inflammation (Xu et al, 2005; Semple et al, 2005).

There is, however, one case report of allergic reaction following use of a combination herbal product containing kudzu (Kakkonto). Another report suggests that taking kudzu root by mouth might cause liver damage. In retrospect, my experience demonstrates the utility of kudzu for alcoholism. If I had been committed to using it to wean off of alcohol and then quit, it might have been a very valuable part of my recovery.

How much water should I be drinking?

The responses to comments on fitrecovery.com are designed to support, not replace, medical or psychiatric treatment. My standards for categorizing an herb or drug as a “miracle” supplement are quite high. Something has to create a massive increase in sense of well-being to fit into this category. While it does not quite make the cut, it is definitely worth trying if you’re looking to cut down on or quit drinking. However, there are a lot of supplements that claim to contain it that are mostly cheap fillers.

Kudzu root extract is now widely used in the United States as a natural remedy for alcoholism. Modern clinical studies of kudzu and other herbal products tend to be flawed by large dropout rates, no measures of medication adherence, relatively few assessments, and no information on the source or dose of the preparation. We have analyzed a variety of commercial kudzu preparations and found them to vary widely in their isoflavone concentrations, even within the same manufacturer. These issues highlight the difficulties of evaluating the efficacy of dietary supplements.

Kudzu and Heart Disease

Kudzu contains compounds that are believed to reduce alcohol cravings and help with withdrawal symptoms. Amount of beer consumed during drinking session after either placebo or puerarin treatment for 7 d. The use of complementary and alternative therapies has increased at an explosive pace (Barnes et al, 2008).

kudzu extract for alcoholism

Day 8 always consisted of a placebo (orange juice only) drink challenge, while day 9 consisted of an alcohol drink challenge of either the high or low dose depending on group randomization. Participants were told only that the drinking sessions could be with placebo, or a low or high dose of alcohol. The drinks were administered between 2 and 2.5 hours after consumption of the morning dose of medication as blood levels https://ecosoberhouse.com/ of puerarin peak at this time (Penetar et al., 2006). Participants continued to take their medication through the morning of day 9 prior to the alcohol drink challenge. Following the first set of challenge sessions, there was a 1 month ‘washout’ period during which no medication was taken. This washout period provided ample time to eliminate pharmacodynamic interactions between kudzu and placebo treatment conditions.